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Image intensification:
X-rays are also used in real-time procedures such as angiography or contrast studies of the hollow organs (e.g. barium enema of the small or large intestine) using fluoroscopy acquired using an X-ray image intensifier. Angioplasty, medical interventions of the arterial system, rely heavily on X-ray-sensitive contrast to identify potentially treatable lesions.
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Diagnostic radiography |
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Radiography is the use of ionising electromagnetic radiation to view objects. The modification of objects with radiation is not radiography. In cases of modification, when the object is a human or an animal and the purpose is a cure of disease, it is radiotherapy (or in a few cases a criminal act and when the object is not living it could be food irradation or some other form of radiation processing.
Projection radiography
The creation of images by exposing an object to X-rays or other high-energy forms of electromagnetic radiation and capturing the resulting remnant beam (or "shadow") as a latent image is known as "projection radiography." The "shadow" may be converted to light using a fluorescent screen, which is then captured on photographic film, it may be captured by a phosphor screen to be "read" later by a laser (CR), or it may directly activate a matrix of solid-state detectors (DR--similar to a very large version of a CCD in a digital camera). Bone and some organs (such as lungs) especially lend themselves to projection radiography. It is a relatively low-cost investigation with a high diagnostic yield.
Projection radiography uses X-rays in different amounts and strengths depending on what body part is being imaged:
* Hard tissues such as bone require a relatively high energy photon source, and typically a tungsten anode is used with a high voltage (50-150 kVp) on a 3-phase or high-frequency machine to generate braking radiation. Bony tissue and metals are denser than the surrounding tissue, and thus by absorbing more of the X-ray photons they prevent the film from getting exposed as much. Wherever dense tissue absorbs or stops the X-rays, the resulting X-ray film is unexposed, and appears translucent blue, whereas the black parts of the film represent lower-density tissues such as fat, skin, and internal organs, which could not stop the X-rays. This is usually used to see bony fractures, foreign objects (such as ingested coins), and used for finding bony pathology such as osteoarthritis, infection (osteomyelitis), cancer (osteosarcoma), as well as growth studies (leg length, achondroplasia, scoliosis, etc).
* Dental radiography uses a small radiation dose with high penetration to view teeth, which are relatively dense. A dentist may examine a painful tooth and gum using X-ray equipment. The machines used are typically single-phase pulsating DC, the oldest and simplest sort. Dental technicians or the dentist may run these machines-- radiologic technologists are not required by law to be present.
* Mammography is an X-ray examination of breasts and other soft tissues. This has been used mostly on women to screen for breast cancer, but is also used to view male breasts, and used in conjunction with a radiologist or a surgeon to localise suspicious tissues before a biopsy or a lumpectomy. Breast implants designed to enlarge the breasts reduce the viewing ability of mammography, and require more time for imaging as more views need to be taken. This is because the material used in the implant is very dense compared to breast tissue, and looks white (clear) on the film. The radiation used for mammography tends to be softer (has a lower photon energy) than that used for the harder tissues. Often a tube with a molybdenum anode is used with about 30 000 volts (30 kV), giving a range of X-ray energies of about 15-30 keV. Many of these photons are "characteristic radiation" of a specific energy determined by the atomic structure of the target material (Mo-K radiation).
Fluoroscopy (angiography, gastro-intestinal fluroscopy)
For main article see X-ray image intensifier and Contrast medium
Fluoroscopy is a term invented by Thomas Edison during his early X-ray studies. The name refers to the fluorescence he saw while looking at a glowing plate bombarded with X-rays.
This is a technique that provides moving projection radiographs of lower quality. Fluoroscopy is mainly performed to view movement (of tissue or a contrast agent), or to guide a medical intervention, such as angioplasty, pacemaker insertion, or joint repair/replacement. The latter are often carried out in the operating theatre, using a portable fluoroscopy machine called a C-arm. It can move around the surgery table and make digital images for the surgeon.
Angiography is the use of fluoroscopy to view the cardiovascular system. An iodine-based contrast is injected into the bloodstream and watched as it travels around. Since liquid blood and the vessels are not very dense, a contrast with high density (like the large iodine atoms) is used to view the vessels under X-ray. Angiography is used to find aneurysms, leaks, blockages (thromboses), new vessel growth, and placement of catheters and stents. Balloon angioplasty is often done with angiography.
Fluoroscopy can be used to examine the digestive system using a substance which is opaque to X-rays, (usually barium sulphate or gastrografin), which is introduced into the digestive system either by swallowing or as an enema. This is normally as part of a double contrast technique, using positive and negative contrast. Barium sulfate coats the walls of the digestive tract (positive contrast), which allows the shape of the digestive tract to be outlined as white or clear on an X-ray. Air may then be introduced (negative contrast), which looks black on the film. The barium meal is an example of a contrast agent swallowed to examine the upper digestive tract. Note that while soluble barium compounds are very toxic, the insoluble barium sulfate is non-toxic because its low solubility prevents the body from absorbing it.
Most modern injected radiographic positive contrast media are iodine-based. Patients who suffer from allergy to shellfish may be allergic to iodine, and should consult their physician regarding pre-medication to lessen risk of allergic reaction. Iodinated contrast comes in two forms: ionic and non-ionic compounds. Non-ionic contrast is significantly more expensive than ionic (approximately three to five times the cost), however, non-ionic contrast tends to be safer for the patient, causing fewer allergic reactions and uncomfortable side effects such as hot sensations or flushing. Most imaging centers now use non-ionic contrast exclusively, finding that the benefits to patients outweigh the expense.
* Negative radiographic contrast agents are air and carbon dioxide (CO2). The latter is easily absorbed by the body and causes less spasm. It can also be injected into the blood, where air absolutely cannot.
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